Gendone 君德同创

Our Values

Industrial Base

We are the first company to research and produce Guanidinoacetic Acid (GAA).

Gu an Gendone Industrial Base, the world's largest GAA production hub, houses three key production workshops: granulation workshop, synthesis workshop and coating workshop.

Patents & Certificates

Gendone initiated the process of patenting various aspects of the chemical synthesis and production processes of GAA since 2009.

1New Product Certificate
2Announcements of Ministry of Agriculture and Rural Affairs of the PRC
7Qualifications
12National Support for Gendone's GAA Project
37Patents
117Test Reports

ISO 9001
ISO 22000
FAMI - QS
HALAL
FSMA
KOSHER
TFS

Gendone established Chinese Standard of GAA

Gendone has established 45 indicators, secured the group standard accreditation from the Zhongguancun Standardization Association (ZSA) for Feed Additive Guanidinoacetic Acid （ GAA ） (T/ZSA 219-2024), which is the current Chinese Standard of GAA.

	EFSA	MAFF	FDA	CHINA (Gendone)
Cyanamide (%)	≤0.03	≤0.03	≤0.01	≤0.03
Dicyandiamide (%)	≤0.5	≤0.5	≤0.5	≤0.5
Melamine (mg/kg)	≤20	≤20	≤15	≤10
Total Triazine (mg/kg)	--	--	≤35	≤35
Dioxin (pg TEQ/kg)	≤750	--	--	≤500

GAA White Paper

In celebration of Gendone's 20th anniversary, we proudly unveil the White Paper on Theoretical Research and Industrialization Development on Guanidinoacetic Acid. This comprehensive document showcases Gendone's 17-year journey of theoretical exploration and practical application in GAA, offering invaluable insights to the global feed and breeding industries.

Practical Application Values

2.1 Practical Application Values of NutriBuilder

2.1.1 Improve body weight and FCR

NutriBuilder supplementation can increase the final body weight of poultry by 50-100g and decrease the FCR by more than 0.05, increase the ADG of swine by more than 50 g and decrease by more than 0.2.

Animal	Treatment	Body weight	FCR
AA broilers	600 g/t NutriBuilder, 42 days	Final body weight:2.72 kg vs 2.95 kg	1.75 vs 1.65
Finishing pigs	500 g/t NutriBuilder, 50 days before slaughter	ADG: 1041 g vs 1098 g	3.15 vs 2.98

2.1.2 Improve slaughter performance and meat quality

NutriBuilder can increase dressing percent by 1.5% and decrease drip loss by 1%. Animal Treatment Slaughter performance Meat qualit.

Animal	Treatment	Slaughter performance	Meat quality
AA broilers	600 g/t NutriBuilder, 42 days	BI:18.2 vs 18.8, AI:1.35 vs 1.28	SF:12.5 vs 10.8
Finishing pigs	600 g/t NutriBuilder, 60 days before slaughter	Lean meat percentage: 55.37% vs 60.85%	Drip loss: 4.65% vs 3.45%

2.1.3 Spare energy

NutriBuilder can reduce cost by spare 100 kcal/kg ME for poultry.

Animal	Treatment	Effects (control group vs treatment group) ADGFCR
Ross 308 broilers	600 g/t NutriBuilder, s 100 kcavedal/kg ME, 40 days	66.8 g vs 67.4 g	1.673 vs 1.676

2.1.4 Spare protein

NutriBuilder can reduce cost by spare 0.5% crude protein.

Animal	Treatment	Effects (control group vs treatment group) Body weight gainFCR
Ross 308 broilers	600 g/t NutriBuilder, saved 0.5% CP, 42days	2564 g vs 2610 g	1.71 vs 1.65

2.1.5 Spare Arginine

NutriBuilder can reduce cost by spare arginine.

Animal	Treatment	Effects (control group vs treatment group) Body weight gainFCR
Ross 308 broilers	670 g/t NutriBuilder, spare 1000 g/t Arginine, 32 days	3142 g vs 3132 g	1.510 vs 1.527

2.1.6 Replace fish meal

NutriBuilder can replace fish meal.

Animal	Treatment	Effects (control group vs treatment group) ADGGain:feed, g/kg
Ross 308 broilers	1200 g/t NutriBuilder, replace 70 kg/t fish meal, 28 days	53.9 g vs 51.4 g	748.5 vs 740.2

2.1.7 Improve growing performance on low-energy diet

The treatment group diet reduce by 50 kcal/kg metabolic energy (Poultry) than the control group diet.

Animal	Treatment	Effects (control group vs treatment group) Feed Intake/ bird(kg)BW （kg）FCREPI
Cherry valley duck	600 g/t NutriBuilder, 38 days	5.16 vs 5.15	2.90 vs 2 .94	1.78 vs 1.75	436.57 vs 445.97

The treatment group diet reduce by 50 kcal/kg metabolic energy (Poultry) than the control group diet.

Animal	Treatment	Effects (control group vs treatment group) Initial BW (g)Final BW (kg)Feed intake (kg)FCREPI
Cherry valley duck	600 g/t NutriBuilder, 24 days	51 vs 51	2.69 vs 2.77	1.78 vs 1.75	1.87 vs 1.76	341.97 vs 384.07

The treatment group diet reduce by 75 kcal/kg net engery (swine) and 0.5% crude protein than the control group.

Animal	Treatment	Effects (control group vs treatment group) Initial BW (g)Final BW (g)ADFI (g/d)ADG (g/d)FCR
Finishing pigs	500 g/t NutriBuilder, 37 days	83.95 vs 84.46	130.1 vs 130.48	3554 vs 3572	1247 vs 1244	2.85 vs 2.88

The treatment group diet reduce by 50 kcal/kg metabolic energy (Poultry) than the control group diet.

Animal	Treatment	Effects (control group vs treatment group) Final BW(g)Feed intake (g)Feed to weight RatioBrisket (g) Leg meat (g)Abdo- minal fat (g)Edible parts (g)
Ross 308 broilers	600 g/t NutriBuilder, 32 days	1906^b vs 1981^a	2723 vs 2731	1.429^a vs 1.380^b	412.5^b vs 442.5^a	423.1^b vs 439.4^a	80.00^b vs 71.25^a	1272^b vs 1316^a

2.1.8 Improve performance of layers

Animal	Treatment	Effects (control group vs treatment group) FW(kg)Laying rate(%)
66 weeks old Hy-Line brown layers	600 g/t NutriBuilder, 30 days	2.11 vs 2.23	80.3% vs 81.9%

2.1.9 Improve performance of breeders

Animal	Treatment	Effects (control group vs treatment group) Fertility(%)Hatchability (%)
42 weeks old AA breeders	1000 g/t NutriBuilder, 28 days	86.6% vs 91.0%	85.1% vs 86.6%

2.2 Practical Application Values of CreBuilder

2.2.1 Functions of CreBuilder on Cows

Improve lactation performance, nutrient digestion and ruminal fermentation in Holstein dairy cows.

Animal	DM intake （kg/d）	Milk production（kg/d）	Milk fat（kg/d）	Milk lactose（kg/d）	Milk/DM intake（kg/kg）
600 g/t CreBuilder	19.3 vs 20.3	29.5 vs 33.9	1.02 vs 1.25	1.55 vs 1.74	1.52 vs 1.66

Improve total tract nutrient digestibility and rumen fermentation in Holstein dairy cows.

Treatment	pH	Total VFA(Mol/100mmol)	Acetate:Propionate
600 g/t CreBuilder	6.76 vs 6.57	128 vs 145	2.82 vs 2.49

2.2.2 Functions of CreBuilder on Beef cattle

Improve growth performance, nutrient digestion and feed conversion efficiency of Angus steers.

Treatment	ADG(kg/d)	ADG/DMI	Acetate:Propionate	Feces N(g/d)
800 g/t CreBuilder	0.9 vs 1.05	0.09 vs 0.11	4.35 vs 3.65	39.27 vs 34.29

2.2.3 Functions of CreBuilder on Sheep

Improve growth performance, nutrient digestion, carcass traits and meat quality and feed conversion efficiency of Dorper lambs.

Treatment	Final BW(kg)	ADG(g/d)	FCR
900 g/t CreBuilder	40.64 vs 44.18	226.52 vs 280.52	6.41 vs 5.76

Improve slaughter performance of lambs.

Treatment	Carcass weight/kg	Net meat weight/kg	Net meat percentage/%	Eye muscle area/cm
900 g/t CreBuilder	20.00^b vs 22.68^a	13.64^b vs 16.11^a	35.25^b vs 37.54^a	14.33^b vs 16.43^a

Improve meat quality of lambs.

Treatment	pH(24 h)	L(24h)	Water holding capacity/%	Eye muscle area/cm
900 g/t CreBuilder	5.49^b vs 5.7^a	31.39^b vs 32.82^a	48.81^b vs 51.90^a	14.33^b vs 16.43^a

2.3 Practical Application Values in fish Aqua Animals

Animal	Treatment	Body weight gain	FCR and SGR
Nile Tilapia Fish	600 g/t NutriBuilder, 60 days	30.38 g vs 35.53 g	FCR:2.13 vs 2.00; SGR:1.47 vs 1.53

Gendone VS Other Factories

3.1 The least residue content in products.

The test report of GAA products of different manufacturers from third-party laboratories.

Manufacturer	GAA (%)	Cyanamide (mg/kg)	Dicyandiamide (mg/kg)	Glycine (%)	Melamine (mg/kg)
Gendone	98.22	ND	76	ND	ND
Local A	95.18	14873.5	2681.6	3.63	38.21
Local B	93.17	23318.78	3189.75	4.17	80.43
Local C	86.44	24419.18	3019.05	10.40	73.43

3. 2 Harm of Poor-quality GAA

There are lots of residues on Poor quality GAA products, which would cause the following issue.

Harm of residues in GAA products

Items	Conclusion
Cyanamide	Highly toxic; LD50 142—223mg/kg for rat. Adverse health effects like weight loss, hypothyroidism, arched back, tremor, coarse fur and oxidative stress, dyspnea and cyanamide flush (red skin)
Dicyandiamide	LD50 ＞ 5000 mg/kg for rat. Degrade into gaseous hydrogen cyanide in stomach, cause and aggravate respiratory diseases; bitter taste results in decrease of feed intake.
Melamine	Accumulated in the kidney. Renal injury kidney stone, obstructive acute renal failure etc.
Dioxin	Carcinogen; highly toxic substances. Dioxin will accumulate in the food chain and eventually exist in fat tissues. The poor- quality GAA often contents a large amount of dioxins, which leads to the accumulation of dioxin in foods such as meat, eggs, milk and so on. And then damage peoples health.

3.3 Our innovation: Powder to Granule

The contrast of Powder to Granule

Items	Powder	Granule （NutriBuilder）
Free-flowing	Poor	Good
Dust pollution	High	NO
Moisture absorption and caking	Yes	NO
Processing uniformity	Poor	Good