New Advances in Feed Safety and Efficiency Gendone Shares GAA Research Findings

Focus on Product Quality and Safety

The GAA market is uneven in quality. Low-grade products with excessive harmful impurities such as cyanamide, dicyandiamide, melamine, and dioxins can depress feed intake, roughen feathers or coats, reduce body weight, induce hypothyroidism, cause paler meat, and even lead to hepatic and renal failure. Residues may remain in animal tissues and threaten consumer health.

Gendone tested GAA products from multiple manufacturers collected from the market. Results showed that the majority contained seriously excessive levels of harmful impurities, posing risks to animal production and human safety.

In his report, Dr. Yang Libin, Chairman of Gendone, shared these findings to give stakeholders a clear view of real-world impurity control and to provide a reference for recognizing quality differences and potential safety risks among GAA products.

Mixing Uniformity and Dusting Loss: QC Findings

Gendone’s QC team at the Research Institute evaluated commercial complete feeds, 20% concentrates, and 4% premixes. Using a three-factor, three-level orthogonal design, the team measured mixing uniformity and dusting loss rate.

Key results:

In complete feed and concentrate, powder and powder + pellet composite formulations failed to meet the target coefficient of variation (CV) for mixing uniformity.

In premix, CV differences between the two formulations were less pronounced, but dusting loss remained significantly higher than that of pellet products.

Toxicology: Impact of GAA Impurities

Gendone, together with the Poultry Nutrition and Feed Innovation Team at the Feed Research Institute of the Chinese Academy of Agricultural Sciences, conducted two studies:

Effects of GAA impurities on chick hatchability, early growth, and hepatic/renal injury

Dose–response study on how combined GAA impurities affect broiler growth and development

Findings:

Cyanamide shows strong lethality and marked developmental toxicity and warrants the highest level of attention.

Dicyandiamide can cause embryo death at high doses.

When impurity load exceeds 5× the reference limit (cyanamide 300 mg/t; dicyandiamide 600 mg/t used as benchmarks), broiler growth is severely suppressed. Body weight reached only about 70% of the blank control, 1×, or 5× groups under comparison.

The growth-inhibiting effect of excess impurities begins from the chick stage and shows a partial cumulative trend over time.

Technology Innovation and Value Extraction

Based on high-purity GAA monomer, Gendone announced two cost-saving, efficiency-enhancing composite application programs at the forum: Yiben™ and Zhuangmeijian®. These programs aim to unlock GAA’s value in improving feed utilization and reducing total farming costs more effectively.

Joint Trial in Beef Cattle

Dr. Yang also presented joint results with Professor Zhou Zhenming’s team at the Beef Cattle Research Center, China Agricultural University. The study confirmed that appropriately dosing coated GAA in beef cattle diets significantly improves key production indicators, including growth performance, digestibility, and blood metabolism. This not only elevates farm economics but also supports meat quality and food safety.

Ongoing Commitment

Gendone remains committed to the R&D and safe application of feed additives. The work shared at this forum is a milestone update from our collaborations with research partners. We look forward to advancing feed technology and standardization together with industry colleagues, contributing to the healthy development of animal husbandry and to food safety.