CreBuilder® is the latest rumen-protected guanidinoacetic acid (GAA) developed by Beijing Gendone Biotechnology Co., Ltd. CreBuilder is a nutritional feed additive, which belongs to "amino acid, amino acid salt and its analogues". CreBuilder adopts a microcapsule multilayer coating process, which is an ideal creatine source for high-yield ruminants. CreBuilder supplies more metabolizable guanidinoacetic acid than unprotected products. CreBuilder is used in ruminant feed to ensure adequate supply of creatine, improve energy efficiency, promote protein deposition, improve performance, slaughter performance, and meat quality, and relieve production stress.
Metabolic pathway in vivo
Creatine is a conditionally essential nutrient, whose synthesis requires three amino acids (arginine, glycine and methionine) and three organs (kidney, liver and muscle). In the kidney, arginine transfers its amidino group to glycine to synthesize GAA. Therefore, GAA is the direct endogenous precursor of creatine in the organism. GAA is transferred to the liver, where S-adenosylmethionine(SAM) gives its methyl group to GAA to synthesize creatine. Creatine is then transported by the bloodstream to the target cells with high energy need, such as skeletal muscle, mammary gland, heart, brain, sperm and immune cells. Creatine plays a key role in energy transfer and supply via creatine-phosphocreatine system. Dietary supplemental CreBuilder can increase creatine level in the body by 20%.
Product characteristics
Guanidinoacetic acid content ≥70%;
More than 90% GAA can be protected and can't be destroyed in rumen, thus to absorb in small intestine;
The product is used microcapsule multilayer coating process.
Why do ruminant need CreBuilder® ?
All plant-based diets cannot meet ruminant creatine requirements, resulting in decreased performance;
Unprotected guanidinoacetic acid is quickly degraded by rumen microorganisms as non-protein nitrogen, and rumen by-pass ratio is very low;
CreBuilder provides more metabolizable guanidinoacetic acid.
Advantages
For beef and sheep
Improve the rumen environment, increase weight gain by 8-10%;
Promote muscle growth, reduce fat deposition and significantly improved body shape (thick neck, full hips);
Increase the dressing percentage and net meat rate by1-3%, reduce drip loss and improve meat quality;
Relieve heat stress, transportation stress.
For cow and goat
Improve FCR and nitrogen deposition.
Enhance physical fitness and reduce postpartum metabolic diseases.
Relieve production stress, such as heat stress.
Improve reproductive performance and offspring performance.
Specification
Recommendations
This product can be added to premix, concentrate feed or TMR diet.
